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In general, the potential for inhibition of statin metabolism is as follows: simvastatin and lovastatin > atorvastatin and rosuvastatin >> pravastatin. Interactions of PIs with fluvastatin and pitavastatin have not been studied thoroughly. NNRTIs Pravastatin is excreted to a large extent unchanged in bile and urine, and biliary excretion is the major route of elimination. Main enzymes and associated interactions CYP3A. Pravastatin is not significantly metabolized by the cytochrome P-450 (CYP) enzymes. Translations in context of "interaction between pravastatin" in English-French from Reverso Context: No interaction between pravastatin and INTELENCE is expected.

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Atorvastatin, • Inhibition of CYP 3A4 by imatinib: ↑ atorvastatin exposure9,18,19 • Inhibition of Pgp by atorvastatin: ↑ imatinib exposure9  Jul 20, 2011 Fluvastatin and Pravastatin (both generic) have minimal drug interaction with CNIs/amlodipine and should be considered for mild  Apr 21, 2013 Pravastatin (Pravachol) appears to have the least effect in reducing CoQ10 levels in the body. Many commonly used medications interact with  Aug 5, 2020 Pravastatin (Pravachol) It's packed with dosing info, drug interactions, clinical pearls, and all sorts of other goodies (including a breakdown of  Jun 19, 2018 Pravastatin Dosage and side effect discussed.Slides covered include:What is PravastatinUses forDosageSide EffectsPravastatin interactions. Jan 23, 2018 Your Medication PravastatinPravastatin is also known as the brand names: PravacholPravastatin comes in 10mg, 20 mg, 40mg, 80mg tablets. May 3, 2016 0.6%; pravastatin, 0.2%; rosuvastatin, 0.1%; fluvastatin, 0.04%; and Behavioral interactions of simvastatin and fluoxetine in tests of anxiety  May 11, 2020 What you eat and drink can cause harmful effects when mixed with certain drugs.


Pravastatin is partially eliminated by the kidney. Drug and/or metabolite accumulation may occur in patients with significant renal impairment, which may increase the risk of adverse effects, including hepatic and musculoskeletal toxicities. Pravastatin has the following interaction information: Acipimox.

Pravastatin interactions

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Pravastatin interactions

Pravastatin (Pravacol) /17%/ Pravastatin. Pravacol. Fluvastatin that interacts with simvastatin to an alternative statin with less  Simvastatin och/eller pravastatin har visats reducera mor- of drug therapy, e.g., adverse event, polypharmacy and interactions, might outweigh the benefits. Although interaction studies with atorvastatin and colchicine have not been with atorvastatin 80 mg and standard degree of lipid lowering with pravastatin. av G Englund · 2005 — conditions or risk of drugYdrug interactions and thereby help to HMG-CoA reductase inhibitors Cerivastatin, pitavastatin (156), pravastatin.

Pravastatin interactions

pravastatin oral brand names and other generic formulations include: Pravachol Oral. All generic drug interactions for pravastatin oral (lists will include brand and generic names): 1 contraindicated drug interaction. 21 serious drug interactions. 89 significant drug interactions. 7 minor drug interactions. Diltiazem did not affect the oral AUC, Cmax, or half-life of pravastatin.
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The lipid-lowering agent pravastatin and the antidepressant paroxetine are among the most widely prescribed drugs in the world. Unexpected interactions between them could have important public health implications. We mined the US Food and Drug Administration's (FDA's) Adverse Event Reporting System … The binding interactions of simvastatin (SIM), pravastatin (PRA), fluvastatin (FLU), and pitavastatin (PIT) with bovine serum albumin (BSA) were investigated for determining the affinity of four statins with BSA through multiple spectroscopic and molecular docking methods. The experimental results s … com/health/food-and-nutrition/AN00413 Grapefruit juice, and other grapefruit products and certain other citrus fruits can interfere with several kinds of prescription medications. Don't take these interactions lightly, as some can cause potentially dangerous health problems.

6 Oct 2019 Statins have terminal elimination half‐lives that range from less than 5 hours for fluvastatin, lovastatin, pravastatin and simvastatin, to 13 hours for  If you also take certain other drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take pravastatin at least 1 hour before  We review and highlight major drug-drug interactions between statins and antibacterial and Pravastatin, and pitavastatin are not substrates of CYP450 [ 11,12].
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Sveriges lantbruksuniversitet - Primo - SLU-biblioteket

Clin Pharmacol Ther 2011 Jul;90(1):133-42. 31 minor drug interactions.

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An interaction is when a substance changes the way a drug works. This can be harmful or prevent Pravastatin Interactions with Food and Herbs Fatty Foods: Fatty foods may decrease the effectiveness of pravastatin in lowering cholesterol. Pravastatin Interactions with Alcohol Pravastatin and Coadministration of colchicine and rosuvastatin, fluvastatin, lovastatin, pitavastatin, and pravastatin is reasonable when clinically indicated. Dose reductions may be considered for atorvastatin, simvastatin, and lovastatin, given the potential for interactions mediated by both CYP3A4 and permeability glycoprotein (P-gp) pathways.